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All Journal Jurnal Pendidikan dan Pembelajaran SOSIOLOGI IJOG : Indonesian Journal on Geoscience Medical Journal of Indonesia Jurnal Pendidikan Matematika Berkala Ilmu Kesehatan Kulit dan Kelamin Jurnal Pengabdian Kepada Masyarakat Universitas Bangka Belitung Al-Ijtima`i: International Journal of Government and Social Science EDU-MAT: Jurnal Pendidikan Matematika As-syifaa Jurnal Farmasi Jukung (Jurnal Teknik Lingkungan) Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Inovasi: Jurnal Ilmiah Ilmu Manajemen Journal Agriculture Sciences JENIUS (Jurnal Ilmiah Manajemen Sumber Daya Manusia) Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Nusantara Science and Technology Proceedings

Iskandar Zulkarnain

Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta.

Author-ID : 429160

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

Published : 35 Documents Claim Missing Document

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Articles

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Penatalaksanaan Kandidiasis Mukokutan pada Bayi Kusumaputra, Bagus Haryo; Zulkarnain, Iskandar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Latar belakang: Bayi memiliki risiko lebih tinggi terhadap cedera kulit, absorbsi kulit, dan infeksi kulit. Kandidiasis mukokutan pada bayi dapat berupainfeksi yang paling umum seperti kandidiasis oral dan ruam popok, sampai berupa infeksi serius yang berpotensi menjadi infeksi sistemik, seperti kandidiasis kongenital dan dermatitis fungal invasif. Infeksi mukokutan pada bayi prematur dapat menjadi permulaan infeksi sistemik sehingga membutuhkan perhatian khusus.Tujuan: Memberikan pengetahuan mengenai kandidiasis mukokutan pada bayi yang meliputi etiopatogenesis dan manifestasi klinis, sehingga diharapkan dapat memberikan pengobatan yang lebih baik. Telaah kepustakaan: Lokasi utama kontak dengan kandida pada bayi baru lahir yang tersering adalah mukokutan, termasuk saluran pencernaan, pernapasan, dan kulit. Faktor predisposisi kandidiasis meliputi faktor mekanik, nutrisi, perubahan fisiologis, penyakit sistemik, dan faktor iatrogenik. Diagnosis kandidiasis mukokutan berdasarkan pemeriksaan klinis ditunjang dengan pemeriksaan mikroskop langsung dan kultur. Pengobatan kandidiasis mukokutan pada bayi meliputi pengobatan topikal dan sistemik. Golongan antijamur topikal yang digunakan pada kandidiasis antara lain imidazol dan poliene, sedangkan pengobatan antijamur sistemik meliputi flukonazol dan amfoterisin B. Simpulan: Pengobatan kandidiasis mukokutan pada bayi sebagian besar menggunakan obat topikal. Pengobatan sistemik digunakan bila terapi topikal gagal atau pada infeksi kandida yang terdapat gejala sistemik.Kata kunci: kandidiasis mukokutan, bayi, tatalaksana.

Increasing of Skin pH level in Childhood Atopic Dermatitis Primadiarti, Pedia; Rahmadewi, Rahmadewi; Zulkarnain, Iskandar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Background: Atopic dermatitis (AD) has multifactorial etiologies such as genetic, environment, and imbalance of immunology basis.Â AD is marked with skin barrier dysfunction, whichcharacterized by fillagrin mutation. Fillagrin itself has an important role in skin hydration and pH adjustment, so that its functional nor amount defect will lead to hydration and pH adjustment impair, as well as shown in AD phenotype. Purpose: To evaluatethe difference of skin pH in AD (lesional and non lesional area) and normal children. Methods:Â Phase 1 study was descriptive observational study, to determinenormal skin pH in 98 children. The following phase 2 was observational analitic study in 38 AD patients todeterminepH level of atopic group (lesional and non lesional skin).Results: pH level of normal children skin was 4.86Â±0.461, lesional skin in AD was 5.86Â±0.564, and in nonlesional skin was 5.20Â±0.460. One way ANOVA test revealed value p=0.000, post hoc analysis value was p=0.000. Conclusions: Higher pH level was observed on AD patients. Skin pH is an important factor in the pathogenesis of AD, main concern in the treatment of AD is maintaining skin pH, which is important to reduce AD exacerbation.Key words: fillagrin, pH of atopic dermatitis,pH of normal children.

Non Bullous Congenital Ichthyosiform Erythroderma Setyowatie, Lita; Zulkarnain, Iskandar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Background: Non bullous congenital ichthyosiform erythroderma (NBCIE) is an inherited genodermatosis, very rare autosomal recessive inflammatory ichthyosis, chronic, characterized by dryness and scaling. Purpose: To describe the clinical manifestations of NBCIE since it is a rare case, occurs in 1 in 300.000 people. Case: Baby MR 5 month old, Javanese boy, with main complaint white scale and redness patches on almost all of his body since 1.5 month old. Born as collodion baby, then the membrane was slowly thinning and became generalized erythroderma on almost all of his body accompanied with fine white scale, large, thick, plate-like scale only on lower leg. No ectropion and eclabium. No relatives in the pedigree suffer from the same disease. Histopathology examination showed non-bullous congenital ichthyosiform erythroderma. Case management: Emollient after bath and pH balance soap. Conclusions: Diagnosis of NBCIE is established from history taking, clinical features, and histopathology examination. Emollient therapy and pH balance soap will eventually lead to improvement.Key words: non bullous congenital ichthyosiform erythroderma, genodermatosis, collodion baby.

Viral infection proï¬le in Pediatric Dermatology Division clinic of Dermatology and Venereology Outpatient Dr. Soetomo General Hospital Surabaya Prabawaningrum, Kinanti; Zulkarnain, Iskandar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Viral infections are common in children and distributed widely in the world. There are not many studies that discuss the proï¬le of viral infection in children in East Java. Purpose: To evaluate viral infections patients proï¬les in the Pediatric Dermatology Division Dermatovenereology Outpatient Clinic of Dr. Soetomo General Hospital in 2008-2010 including prevalence, demographic data, type of infection, patient complaints, skin lesions and management. Methods: A retrospective study using medical records for the period January 2008-December 2010. Basic data (age , gender), history (chief complaint, began to arise, disease history), examination (morphology) and treatment (therapy, repeat visits) were recorded. Results: Viral infection patients as much as 285 patients (6.5 % of all pediatric patients at URJ). Most found diagnosis is molluscum contagiosum (40.4%), in the age group 5-14 years (68.4 %), highest complaints pimples (42.8 %) , most duration of diseases >10 days (40 %). Most management actions in the cosmetics division (61.1 %). Conclusion: Viral infection patients in Pediatric Dermatology Division clinic of Dermatology and Venereology Outpatient Dr. Soetomo General Hospital Surabaya in 2008-2010 is likely to increase each year and require a more comprehensive management.Key words : viral infection, child, RSUD Dr. Soetomo.

Kesesuaian Gambaran Klinis Patognomonis Infestasi Skabies dengan Kepositifan Pemeriksaan Dermoskop dan Kerokan Kulit Kurniati, Kurniati; Zulkarnain, Iskandar; Listiawan, M. Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Latar belakang: Diagnosis infestasi skabies oleh klinisi umumnya ditegakkan dengan gejala klinis patognomonis skabies. Tetapi gejala skabies seringkali tidak khas akibat adanya kemiripan dengan penyakit lain terutama pada anak-anak dan kondisi imunokompromais, sehingga diagnosis klinis seringkali keliru dan mengakibatkan kesalahan pemberian terapi. Diperlukan penegakan diagnosis definitif untuk menemukan Sarcoptes scabiei (S. scabiei) atau telurnya, yang secara konvensional dapat dilakukan dengan pemeriksaan mikroskopik dari kerokan lesi kulit penderita. Namun metode tersebut tidak praktis, membutuhkan keterampilan khusus, cenderung invasif, seringkali memerlukan beberapa kali kerokan, serta sulit dilakukan pada anak-anak, sehingga diperlukan metode yang mudah, non-invasif, dan akurasi yang baik. Pemeriksaan dermoskop menawarkan solusi tersebut. Tujuan: Mengevaluasi kesesuaian gambaran klinis patognomonis infestasi skabies dengan kepositifan dermoskop dan pemeriksaan kerokan kulit Metode: Studi analitik observasional cross sectional, total sampling dalam satu kali observasi pada 243 populasi terjangkau yang berusia 5-14 tahun di satu pondok pesantren. Terdapat 44 sampel yang memenuhi kriteria penerimaan sampel yang dilakukan anamnesis dan pemeriksaan fisik untuk menentukan gejala klinis patognomonis skabies, selanjutnya diperiksa dengan dermoskop dan mikroskop dari kerokan kulit pada lesi. Analisis hasil dengan menghitung kappa agreement dan nilai prediksi positif. Hasil: Dari 44 sampel didapatkan 25 sampel klinis patognomonis skabies dan 19 sampel klinis non patognomonis skabies. Pemeriksaan dermoskopi ditemukan positif pada 25 sampel dan mikroskopik kerokan kulit positif pada 18 sampel. Kesesuaian dermoskopi dan kerokan kulit adalah 79,5%, kappa 0,601. Simpulan: Dermoskop berpotensi digunakan sebagai alat diagnostik definitif skabies pada lingkungan dengan prevalensi tinggi skabies. Kata kunci: skabies, dermoskop, kerokan kulit.

Retrospective Study: Oral Therapy in Children with Atopic Dermatitis Thohiroh, Asmahani; Zulkarnain, Iskandar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Atopic dermatitis (AD) is an inflammation skin characterized by itchy, chronic, residif; can occur in infant, child, and adult. The therapy for AD are divided into systemic and topical therapy. Systemic therapy includes antihistamine and corticosteroid. Purpose: To evaluate pattern of oral therapy in new child AD patient. Methods: Retrospective study methode was performed by evaluating medical records of new child AD patient who received oral therapy in Pediatric Division, Departement of Dermato-veneorology Dr. Soetomo General Hospital 2010 until 2012. The evaluated data include the patients visitation, age, gender, time visit, patients complain, periode of illness, history of atopy, physical examination, management, and follow up. Results: There were 558 patients (88.9%) of 628 new child AD patients who received oral therapy. Oral therapies were provided in form of antihistamine for 518 patients (92.8%), oral antibiotic for 129 patients (23.1%), and corticosteroid for 40 patients (7.2%). Patients who did not return to the hospital after first visitation were 461 patients (82.6%). Conclusions: Most of the child AD patient got an oral therapy. Most of the oral therapy was antihistamine.Key words: atopic dermatitis, child, oral therapy, retrospective.

Co-Authors Afrian, Chandra Agus Haryanto Agustini Rahmawati, Agustini Ahmad Atiq Aminullah Aminullah, Aminullah Asmahani Thohiroh, Asmahani Asmara, Sakhyan Bagus Haryo Kusumaputra, Bagus Haryo Bustami Rahman Dewi, Winda Evina Eko Tri Sumarnadi Agustinus Haryantini, Haryantini Hasmeinah, Hasmeinah Hendarto Hendarto I Gusti Bagus Wiksuana Ildrem Syafri Ismadi Raharjo, Ismadi Istanto, Kelik Julianti Gunawan Kinanti Prabawaningrum, Kinanti KURNIA KURNIA, KURNIA Kurniati Kurniati Lita Setyowatie, Lita M. Yulianto Listiawan Mega Fatimah Rosana Michael Jeffri Sinabutar Mulyadi Mulyadi Noor Amalia Sari, Noor Nurdin Laugu Pedia Primadiarti, Pedia R.H.H. Nelwan Rachman, Firdaus Rahmadewi Rahmadewi Ramadhani, Tiara Ririn Ririn Rospala Hanisah Yukti Sari Siska Natsir, Siska Soraya Djamilah, Soraya Suhartono, H. Irwan Toruan, Rachel Mia Lorenza Lumban Udin Hasanudin Victor G Simanjunta W, Hestu Nugroho

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